Introduction to pharmaceutical bioinformatics

av Jarl E.S. Wikberg (editor)

Förlagsny häftad bok. Genetta Soft Aktiebolag. 4 uppl. 2020. 566 sidor.

Pharmaceutical Bioinformatics is the study of biological and chemical processes with informatics technologies with the aim to understand how drugs interact with the body, how to discover and develop new drugs, and how to implement and improve pharmaceutical therapies. Focus is on chemical and biological interactions, how to represent and handle biological sequences and chemical structures, and how to derive meaningful numerical representations of drugs and macromolecules for use in pharmaceutical bioinformatics analyses. Covered are also databases, design of experiments, machine-learning, QSAR, proteochemometrics, and semantic Web technologies. To those not familiar with pharmacy the book also introduces the basic concepts of drugs, drug discovery and development, and bioinformatics in general.

The book is authored by researchers actively involved in the development of the new exciting area of pharmaceutical bioinformatics who have longstanding experiences from drug discovery and development at both large and small pharmaceutical companies, and from academic research and education.

The book is intended for the biologist, medical professional, chemist or pharmacist, with an interest in learning how informatics can be used to understand biological processes, aid drug discovery and development, and improve pharmacotherapy. The book is also well suited for students at the undergraduate level having basic knowledge in biology as an introduction to the field.